Lichen sclerosus is an inflammatory condition, and like all inflamed tissues, it does not tolerate events that further exacerbate inflammation.

CO2 and erbium lasers are rarely indicated because they promote regeneration through the inflammatory process.

Lasers can be very useful, however, for tissue regeneration in the vagina, which, being in contact with the vulva, should be in the best possible condition.

Radiofrequency should be carefully evaluated because it induces the production of hard and non-elastic collagen.

LEDs (lights of particular wavelengths used for many years by dermatologists for skin care) can be very useful for reducing inflammation.

Shockwaves induce tissue regeneration and soften tissues; it is a promising technique but needs to be supported by high-quality scientific studies.

Transdermal and transmucosal delivery are methods that facilitate the penetration of topical products through weak currents or microchannels opened with radiofrequency or laser methods.